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Feature Definition and Selection for Epiretinal Membrane Characterization in Optical Coherence Tomography Images

机译:相干断层扫描图像中视网膜膜特征的特征定义和选择

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Optical Coherence Tomography (OCT) is a common imaging technique for the detection and analysis of optical diseases, since it is a non invasive method that generates in vivo a cross-sectional visualization of the retinal tissues. These characteristics contributed to the use of OCT imaging in the analysis of pathologies as, for instance, vit-reomacular traction, age-related macular degeneration or hypertension. Among its applications, OCT imaging can be used in the detection of any present epiretinal membrane section in the retina, a critical issue to prevent further complications caused by this pathology. This work analyzed the main characteristics of the epiretinal membrane to define a complete and heterogeneous set of intensity and texture-based features. Those features were studied using representative selectors, as Correlation Feature Selection (CFS) and Relief-F, to identify the optimal subsets that offer the higher discriminative power. K-Nearest Neighbor (kNN), Naive Bayes and Random Forest were finally tested in a method for the automatic detection of the epiretinal membrane in OCT images. Previous works do not focus on automatic procedures and, on the contrary, depend on manual markers or supervised detections, while our method improves significantly this task by automating the search of the region of interest and the classification of the pixels belonging to that area. The methodology was tested using a dataset of 129 OCT images. 120 samples were equally obtained from those scans, featuring both zones with and without epiretinal membrane. The best results were provided by the Random Forest classifier that, using a window size of 15 pixels, a quantity of 13 histogram bins and 28 features, achieved an accuracy of 93.89%.
机译:光学相干断层扫描(OCT)是检测和分析光学疾病的常用成像技术,因为它是一种非侵入性方法,可在体内产生视网膜组织的横截面可视化图像。这些特征有助于OCT成像在病理分析中的应用,例如,玻璃体视网膜牵引,年龄相关性黄斑变性或高血压。在其应用中,OCT成像可用于检测视网膜中任何当前的视网膜前膜部分,这是防止由这种病理引起的进一步并发症的关键问题。这项工作分析了视网膜前膜的主要特征,以定义出一套完整的,基于强度和纹理的异质性特征。使用代表性的选择器(如相关特征选择(CFS)和Relief-F)研究了这些特征,以识别提供更高判别力的最佳子集。最后,在自动检测OCT图像中的视网膜前膜的方法中,测试了K最近邻(kNN),朴素贝叶斯(Bay)和随机森林(Random Forest)。先前的工作并不专注于自动程序,相反,它依赖于手动标记或监督检测,而我们的方法通过自动搜索感兴趣区域和对该区域的像素进行分类,大大改善了该任务。使用129个OCT图像的数据集对该方法进行了测试。从那些扫描中平均获得了120个样品,其特征是带和不带视网膜前膜的两个区域。随机森林分类器提供了最佳结果,该分类器使用15个像素的窗口大小,13个直方图块和28个特征,实现了93.89%的准确性。

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