Assessment of Cytotoxicity and Oxidative Effect of Bismuth Ferrite (BFO) Harmonic Nanoparticles for Localized DNA Photo-Interaction

摘要

Bismuth Ferrite nanoparticles have been recently used to selectively interact with malignant cell DNA via in situ generated second harmonic in a novel theranostics protocol [Nanoscale 6(5), pp. 2929, 2014]. In this report, we extend the screening of biocompatibility of BFO uncoated nanoparticles and assess the nanoparticle-mediated production of reactive oxygen species as a function of excitation wavelength.