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Transport Study of Levodopa across Blood-Brain Barrier (BBB)In Absence or Presence of Various Bile Salts

机译：缺乏或存在各种胆汁盐时左旋多巴跨血脑屏障（BBB）的转运研究

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The purpose of this study was to develop an in vitroblood-brain barrier (BBB) model from co-cultureimmortalized rat brain endothelium cells (RBE4) with ratastrocytes, also to investigate transport of levodopa acrossthis developed model in the absence or presence of bilesalts.

机译：这项研究的目的是开发一种体外共培养的血脑屏障（BBB）模型大鼠永生化大鼠脑内皮细胞（RBE4）星形胶质细胞，也用于研究左旋多巴跨在没有或没有胆汁的情况下这种发达的模型盐。

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《》|2009年|p.1-2|共2页
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Yong Zhi Zhou; Raid G Alany; Sophie Baxter; Jingyuan Wen;
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中图分类药学;诊断学;
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专利

1. A novel family of diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles. [J] . Meritxell Teixido, Esther Zurita, Roger Prades Advances in Experimental Medicine and Biology . 2008,第Null期

机译：一种新的二酮哌嗪类家族，可作为研究跨血脑屏障（BBB）的运输工具及其作为BBB穿梭药物的潜在用途。
2. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice. [J] . Uchida Y, Ohtsuki S, Kamiie J, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2011,第2期

机译：血脑屏障（BBB）药动学：基于BBB转运蛋白的浓度，体外固有转运活性以及小鼠血浆和脑中未结合的部分，重建11种P-糖蛋白底物的体内脑分布。
3. The effect of blood-brain barrier (BBB)-specific laminins for barrier function with a new in vitro BBB model incorporating multi-culturing system of BBB components [J] . Y. Takeshita, S. Fujikawa, M. Omoto, Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology . 2017,第期

机译：血型脑屏障（BBB）特异性层压族屏障功能的影响，具有掺入BBB组分多培养系统的新型体外BBB模型
4. Transport Study of Levodopa across Blood-Brain Barrier (BBB) In Absence or Presence of Various Bile Salts [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：在缺乏或存在各种胆汁盐的情况下血脑屏障（BBB）左旋多巴的运输研究
5. Examining the integrity of the blood-brain barrier (BBB) and the use of lysophosphatidic acid (LPA) to modulate the barrier properties. [D] . On, Ngoc H. 2012

机译：检查血脑屏障（BBB）的完整性以及使用溶血磷脂酸（LPA）调节屏障的性质。
6. Setting-up an In Vitro Model of Rat Blood-brain Barrier (BBB): A Focus on BBB Impermeability and Receptor-mediated Transport [O] . Yves Molino, Françoise Jabès, Emmanuelle Lacassagne, 2014

机译：建立大鼠血脑屏障（BBB）的体外模型：专注于血脑屏障的抗渗透性和受体介导的运输。
7. Setting-up an In Vitro Model of Rat Blood-brain Barrier (BBB): A Focus on BBB Impermeability and Receptor-mediated Transport [O] . Yves Molino, Françoise Jabès, Emmanuelle Lacassagne, 2014

机译：在体外设置A型血脑屏障模型（BBB）：对BBB不渗透性和受体介导的运输的关注

Transport Study of Levodopa across Blood-Brain Barrier (BBB)In Absence or Presence of Various Bile Salts

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