Preparation and characterization of Long Circulating Nanoemulsion for Passive Tumor Targeting

摘要

Long circulating nanoemulsion (NE) formulation for passive tumor targeting of chlorambucil (CLB) was prepared. The encapsulation efficiency, particle size and long term stability of the drug were evaluated. Stable nanoemulsion formulations of chlorambucil having mean size range of 170 nm were obtained. More than 90% chlorambucil was encapsulated in the nanoemulsion.