Characterization of mucoadhesive chitosan-poly(acrylic acid) microspheres by interpolymercomplexation and solvent evaporation method

机译：共聚物复合和溶剂蒸发法表征黏膜黏附性壳聚糖-聚丙烯酸微球

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Interpolymer complex formation betweenpoly(acrylic acid) (PAA) and chitosan was usedto prepare mucoadhesive microspheres bysolvent evaporation method in n-hexane.Enrofloxacin was loaded as a model drug. Theyshowed spherical shape and smooth surface.These microspheres showed strong interactionwith mucin and pH dependent release rate.

机译：互聚物之间形成络合物使用了聚丙烯酸（PAA）和壳聚糖通过制备粘膜粘附微球在正己烷中的溶剂蒸发方法。恩诺沙星用作模型药物。他们呈球形，表面光滑。这些微球表现出强烈的相互作用黏蛋白和pH依赖的释放速率。

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《Annual meeting exposition of the Controlled Release Society》|2005年|1-2|共2页
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Jin-Woo Kim; Hoo-Kyun Choi;
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中图分类药学;
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入库时间 2022-08-26 14:53:51

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Characterization of mucoadhesive chitosan-poly(acrylic acid) microspheres by interpolymercomplexation and solvent evaporation method

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