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Microencapsulation of Antibodies in PCL and PCL-PEG Block Copolymers

机译:PCL和PCL-PEG嵌段共聚物中抗体的微囊化

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PCL and PCL-PEG block polymers were used formicroencapsulation of human IgG by spray drying andsolvent evaporation. Formulations were characterized andtested for immunoreactivity. Spray dried formulationsresulted in improved loading of IgG but had high residualPVA content. The residual organic solvent was withinacceptable limits for all the formulations.
机译:PCL和PCL-PEG嵌段聚合物用于 通过喷雾干燥和 溶剂蒸发。对配方进行了表征并 测试免疫反应性。喷雾干燥制剂 改善了IgG的负载量,但残留量很高 PVA含量。残留有机溶剂在 所有配方的可接受极限。

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