Latent release of IGF-I from PLGA microspheres for tissue engineering applications

摘要

Temporal gradients of growth factor release arebecoming important in tissue engineeringapplications. In this study we encapsulated insulinlikegrowth factor (IGF-I) in PLGA microspheres andshowed that its release can be significantlyattenuated for up to 10 days by incorporating bovineserum albumin.