PLGA-BASED MICROSPHERES FOR THE CONTROLLED RELEASE OF PROTEINSWITHIN TISSUE EQUIVALENTS

摘要

A promising approach to control the concentration ofsignalling molecules within tissue engineered scaffoldsconsists in entrapping biodegradable microspheres thatrelease the protein locally for long time-frames. In thiswork release kinetics of protein-loaded PLGAmicrospheres in collagen-based scaffolds have beeninvestigated.