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BASF Polymers in Film Development Technology for Drug Delivery Applications

机译:巴斯夫聚合物在薄膜开发技术中的应用

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The objective of this study was to evaluate the films ofBASF’s water soluble high molecular weight Kollidon?polymers (Polyvinylpyrrolidones, PVP) alone or incombination with other polymers including KollidonVA64, Kollicoat? IR, Kollidon SR, and Kollicoat MAE100P. A number of formulations were prepared and therectangular polymeric strips approx. 7 cm2 areas wereevaluated for film thickness, elongation, flexibility anddisintegration characteristics. The strips were alsoevaluated for their ability to carry Ibuprofen andDiphenhydramine as the model drugs for intra oraldelivery
机译:这项研究的目的是评估电影 巴斯夫水溶性高分子量Kollidon? 聚合物(聚乙烯基吡咯烷酮,PVP)单独或以 与其他聚合物(包括Kollidon)的组合 VA64,Kollicoat?红外,Kollidon SR和Kollicoat MAE 100P。制备了许多制剂,并且 矩形聚合物条面积为7平方厘米 评估了薄膜的厚度,伸长率,柔韧性和 崩解特性。条也 评估他们携带布洛芬和 苯海拉明为口服的模型药物 交货

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