As Terahertz Pulsed Imaging (TPI) is a non-ionising and non-destructive, three-dimensional technique it can be used for studying hard tissues without requiring sample sectioning, unlike for example, Transmission Micro-radiography (TMR). If TPI can measure the depths of demineralised lesions in teeth samples accurately, the same samples could be re-used and re-measured during in vitro and in situ studies on de- and/or re-mineralization. In this study we compare TPI and TMR for the measurement of the depths of a range of artificially-induced lesions in vitro. Detailed analysis of the results and theoretical considerations reveal how the "Gold Standard" TMR depths can be determined non-invasively to within 5% using TPI.
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