Double-Ballooned Local Drug Delivery Catheter with Blood Bypassing Function

摘要

We present a double-ballooned catheter that enables both local drug delivery and blood bypassing at the same time. Such catheters are targeted for high-dose local drug treatment of cardiovascular diseases, such as atherosclerosis and restenosis, allowing for extended use without causing downstream ischemia. The device is composed of two flexible balloons that can isolate the lesion under inflation. Local drug delivery can be achieved using the inner catheters while a blood bypassing catheter allows for continuous blood flow. The functionalities of the catheter are validated in both benchtop and live pig experiments.