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Comparison of Neural Biomarker Assessment Methods for Early Detection of Alzheimer's Disease

机译:早期发现阿尔茨海默氏病的神经生物标记物评估方法的比较

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With growing age, the cognitive ability degrades gradually as an aging factor. For a portion of people, the cognitive capability diminishes to a great extent, which will eventually result in Alzheimer's disease (AD). Mild cognitive impairment (MCI) is considered as an intermediate stage of AD. Diagnosis of AD patients at an early stage can reduce the chance of developing into a severe condition for cognition. This study aims to investigate the MCI assessment methods (statistical analysis and individual classification) for distinguishing the healthy control (HC) and MCI patients via functional near-infrared spectroscopy (fNIRS). This study evaluated ten digital biomarkers from three brain regions and three mental tasks (
机译:随着年龄的增长,认知能力会随着年龄的增长而逐渐下降。对于一部分人而言,认知能力在很大程度上下降,最终将导致阿尔茨海默氏病(AD)。轻度认知障碍(MCI)被认为是AD的中间阶段。早期诊断AD患者可以减少发展为严重认知状况的机会。这项研究旨在调查通过功能近红外光谱(fNIRS)区分健康对照(HC)和MCI患者的MCI评估方法(统计分析和个人分类)。这项研究评估了来自三个大脑区域和三个智力任务的十种数字生物标志物(

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