Genome wide computational identification of regulatory RNAs in rice plant pathogen Xanthomonas oryzae

摘要

Xanthomonas oryzae is a gram negative bacterial phytopathogen which causes leaf blight disease of rice plant, posing serious threat to the plants and their yield. Regulatory RNAs are heterogeneous functional RNA molecules which modulate/regulate gene expression, thus controlling a wide variety of physiological functions. As an effort to understand the role of regulatory RNAs in the physiology and pathogenesis of Xanthomonas oryzae, we identified candidate regulatory RNAs, such as riboswitches (Cobalamin, FMN, Glycine, SAM, TPP, crcB), small RNAs (asX1, asX3, asX4, sX2, sX5, sX6, sX7, sX9, sX11, sX12, sX13, sX14, Xool, Xoo2, Xoo5, Xoo8) and ribozyme (RNaseP_arch), using in silico approach. We also identified the genes regulated by these regulatory RNAs and their role. Keywords: Xanthomonas oryzae; Regulatory RNAs:II. Ribozymes, Riboswitches, sRNA; phytopathogen; Bioinformatics.