Texture Analysis of Brain CT Scans for ICP Prediction

摘要

Elevated Intracranial Pressure (ICP) is a significant cause of mortality and long-term functional damage in traumatic brain injury (TBI). Current ICP monitoring methods are highly invasive, presenting additional risks to the patient. This paper describes a computerized non-invasive screening method based on texture analysis of computed tomography (CT) scans of the brain, which may assist physicians in deciding whether to begin invasive monitoring. Quantitative texture features extracted using statistical, histogram and wavelet transform methods are used to characterize brain tissue windows in individual slices, and aggregated across the scan. Support Vector Machine (SVM) is then used to predict high or normal levels of ICP using the most significant features from the aggregated set. Results are promising, providing over 80% predictive accuracy and good separation of the two ICP classes, confirming the suitability of the approach and the predictive power of texture features in screening patients for high ICP.