Angular domain optical imaging of turbid media using enhanced micro-tunnel filter arrays

摘要

We experimentally characterized the angular distribution and proportion of minimally deviated quasi-ballistic (snake) photons versus multiply scattered photons in a homogenous turbid medium. The study examined the angular distribution of photons propagating through and exiting the highly scattering medium over a narrow range about the axis of a collimated light source in trans-illumination mode. The measurements were made using an angular domain imaging system that employed one of five silicon micro-machined arrays of micro-tunnels each with a range of different acceptance angles and micro-tunnel structures. The balance between quasi-ballistic photons and unwanted multiply scattered photons accepted by the micro-machined angular filters was measured in order to determine the optimum range of acceptance angles for the system. The experiments were performed in tissue mimicking phantoms using a 2-cm thick optical cell with 0.25% Intralipid? and a near infrared laser. This paper also presents experimental results of the angular domain imaging system employing novel micro-tunnel arrays with minimal internal reflection which can accept the non-scattered light exiting from the turbid medium within its small acceptance angle more efficiently. Our experiments reveal that image contrast was improved from 20% to 30% by employing an angular filter array with minimal internal reflection compared to conventional square-shaped filter arrays of identical size.