Modelling of the human blood circulation and detection of pathophysiological symptoms of atherosclerosis in dependence of the arterial blood flow volume and blood pressure

摘要

For the practical research on influences of vascular diseases on the cardiovascular system a torso model is developed that represents all major arteries and veins. The model allows analysing the reaction of vascular diseases on the time-dependant variance of pressure and volume flow distribution. Therefore the passages between arterial and venous vessels are equipped with flow sensors and pressure is detected at key points. In the following, investigations will be described based on simulation of 4 different stress situations of the torso (rest, exercise, brain work, after meal). In addition 4 different diseases (stages of occlusions and cavities) in the carotid artery are simulated and their impact on pressure and flow distribution in the torso will be described.