Nucleotide sequence analysis on the p35 gene of Bombyx mori nuclear polyhedrosis virus

摘要

Sequence analysis on the p35 gene of Bombyx mori nuclear polyhedrosis virus Suzhou strain (BmNPVsu) showed that BmNPVsu p35 gene, encoding 298 ammo acids, was 897 nt. Compared with BmNPVTS, AcNPV, S1NPV, the nucleotide and amino acid homologies were 99.5%, 95.1%, 89.3% and 98.7%, 89.4%, 76.4% respectively, and showed its evolutive conservation. N~(146), S~(202), E~(204), K~(244) of BmNPVTS P35 are replaced by G, N, Q, N of BmNPVsu P35, and S~(222) of BmNPVT3 P35 is deleted in BmNPVsu P35. It was possible that the function and the anti-apoptosis activity of BmNPVsu P35 are similar with those of BmNPVTS P35.