Malignant potential of oral and labial chronic discoid lupus erythematosus: a clinicopathological study of 87 cases

摘要

@@ Aims: To investigate clinicopathological features and identify clinicopathological risk factors for the malignant transformation of oral and labial chronic discoid lupus erythematosus (DIE) in a relatively large number of patients from China. Methods and results: A total of 87 patients with clinical and histopathological diagnosis of DLE between 1993 and 2009 were reviewed retrospectively in our hospital. The average age at diagnosis was 51.7 years, with a male:female ratio of 1:1.8. The lower lip was the most common site (71.3%). We documented six DLE patients with malignant transformation.