Controlled Growth Factor Delivery for Tissue Engineering

摘要

Controlled release of growth factors from polymer scaffolds has been an attractive platform to regenerate tissues or organs in many tissue engineering applications. In this article, we describe potential growth factors and polymers that can be adopted in tissue engineering approaches. In addition, dynamically controlled growth factor delivery, which has not been systematically exploited yet, is also depicted to envision the future perspective of growth factor delivery in tissue engineering as well as in cell transplantation. Development of polymer scaffolds that release growth factors in response to mechanical stimulation could provide a novel means to guide tissue formation in vivo.