A two-year retrospective study on antibiotic regimens used in children with acute perforated appendicitis

摘要

Acute appendicitis is a common surgical disease in children. Standard treatment approach includes surgery and i.v. antibiotics according to local resistance patterns. There are a number of antibiotic regimens currently in use for this disease, however there is no consensus regarding the use of a certain antibiotic protocol. We present our experience with two antibiotic regimens in patients with acute perforated appendicitis over a 2-year time interval. According to our results, there is no clear advantage of using Ertapenem as first- line antibiotic over a combination of Ceftriaxone and Gentamycin. Data regarding local bacterial resistance to antibiotics are also included in the paper.