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Antiviral composition comprising epidermal growth factor receptor inhibitors as an effective component

机译:包含表皮生长因子受体抑制剂作为有效组分的抗病毒组合物

摘要

The present invention relates to the development of an antiviral composition comprising an epidermal growth factor receptor inhibitor as an active ingredient. Extracellular SARS-CoV-2 RNA that measures how much virus is reduced in infected cells by infecting SARS-CoV-2 after treatment with HEK293T cells using a drug library previously used as an epidermal growth factor receptor inhibitor Efficacy was evaluated by analyzing copy number and nucleocapsid protein. Through this, 9 types of epithelial growth receptor inhibitors that are effective in the treatment of SARS-CoV-2 were discovered.
机译:本发明涉及抗病毒组合物的发展,其包含表皮生长因子受体抑制剂作为活性成分。 通过使用以前用作表皮生长因子受体抑制剂抑制剂的药物文库治疗HEK293T细胞在用HEK293T细胞处理后测量感染细胞中减少了在感染的细胞中减少了多少病毒的细胞外的SARS-COV-2 RNA。通过分析拷贝数和 核衣壳蛋白。 通过这一点,发现了9种具有有效治疗SARS-COV-2的上皮生长受体抑制剂。

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