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Celecoxib solid dispersion having improved dissolution rate oral absorption and method for producing the same

机译:Celecoxib具有改进的溶出速率的固体分散体和制造方法

摘要

The present invention relates to a celecoxib solid dispersion with improved dissolution rate and a method for preparing the same, and more particularly, by using cremophor, a nonionic surfactant, using an anionic surfactant that causes conventional stomach and market Compared to celecoxib products, dissolution rate, oral absorption rate, toxicity, efficacy, skin compatibility, and biodegradability have been improved, so it is expected to be usefully utilized in the field of celecoxib drug treatment.
机译:本发明涉及一种具有改进的溶出速率的塞克昔布固体分散体及其制备方法,更具体地,通过使用导致常规胃和市场的阴离子表面活性剂使用Cremophor的方法,与Celecoxib产品相比,溶出速率相比 已经提高了口服吸收率,毒性,疗效,皮肤相容性和生物降解性,因此预计将在Celecoxib药物治疗领域中使用。

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