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METHODS AND TOOLS FOR DETERMINING CLONAL RELATEDNESS AND PREDICTING CLONAL TRAITS
METHODS AND TOOLS FOR DETERMINING CLONAL RELATEDNESS AND PREDICTING CLONAL TRAITS
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机译:用于确定克隆相关性和预测克隆特征的方法和工具
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摘要
The present disclosure provides methods and compositions for generating clonotypes from input nucleic acid sequences. Presently disclosed clonotype generating methods produce accurate and efficient indicators of genetic relatedness and diversity, including for example, of pathogenic organisms such as infectious bacteria. Also provided are primers, kits, and related methods for determining antibiotic susceptibility of a pathogenic organism, such as, for example, Klebsiella, and for treating an infection by one or more pathogenic Discard organisms on the basis of herein disclosed clonotypes and clonotype-generating methods.
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