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Mobilization of transposition factors to enhance genetic and epigenetic variability in populations

机译:动员转子因子,以增强种群的遗传和表观遗传因素

摘要

A method for mobilization of transposable elements is provided. The method comprises the steps of a) providing an inhibitor of DNA methylation and / or an inhibitor of transcription, and b) contacting the cell containing the inactivated transposable element with the inhibitor and measuring the mobilized metastasis Thereby obtaining cells having the factor. In a second aspect of the present invention, a method for increasing genetic and / or epigenetic mutations in a plurality of eukaryotes is provided. The method comprises: i. Providing an inhibitor of DNA methylation and / or an inhibitor of transcription, ii. Contacting the inhibitor with the organism, and iii. And growing the organism.Selection drawing None
机译:提供了一种动员转换元件的方法。该方法包括a)提供DNA甲基化的抑制剂和/或转录抑制剂,B)与含有灭活的转移元件的细胞与抑制剂接触并测量动员转移,从而获得具有因子的细胞。在本发明的第二方面,提供了用于增加多种真核生物中的遗传和/或表观遗传突变的方法。该方法包括:i。提供DNA甲基化和/或转录抑制剂II的抑制剂。使抑制剂与生物和III联系。并生长生物。选择没有

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