Composition for the prevention, improvement or treatment of drug induced nephrotoxicity that contains oleanolic acid acetate as an active ingredient

摘要

The present invention relates to a composition for preventing, ameliorating or treating drug-induced nephrotoxicity, which comprises oleanolic acid acetate as an active ingredient. Specifically, the present invention includes a pharmaceutical composition for preventing or treating drug-induced nephrotoxicity, comprising oleanolic acid acetate or a pharmaceutically acceptable salt thereof as an active ingredient, the active ingredient The present invention relates to a health functional food for preventing or ameliorating drug-induced nephrotoxicity, and an anticancer adjuvant containing the active ingredient. The oleanolic acid acetate of the present invention is derived from natural products, has no side effects, has no cytotoxicity, and is excellent in the effect of preventing, improving and treating nephrotoxicity induced by drugs, particularly platinum anticancer agents. It can be used as a pharmaceutical composition, health functional food and anticancer adjuvant.