首页> 外国专利> COMPOSITION FOR CULTURING PERIPHERAL BLOOD MONOCYTE-DERIVED REGULATORY T CELL AND REGULATORY T CELL CULTURING METHOD USING SAME

COMPOSITION FOR CULTURING PERIPHERAL BLOOD MONOCYTE-DERIVED REGULATORY T CELL AND REGULATORY T CELL CULTURING METHOD USING SAME

机译:培养外周血单核细胞衍生调节性T细胞和调节T细胞培养方法的组合物

摘要

The present invention relates to a composition for culturing peripheral blood monocyte-derived regulatory T cells and a regulatory T cell culturing method using same. More specifically, the present invention relates to a composition for culturing peripheral blood monocyte-derived regulatory T cells, the composition comprising: at least one antibody selected from the group consisting of anti-CD2, anti-CD3, anti-CD7, anti-CD8, anti-CD28, anti-CD30L, anti-CD40, anti-CD70, anti-CD80, anti-CD83, and anti-CD86; at least one cytokine selected from the group consisting of interleukin-2, interleukin-4, interleukin-7, interleukin-12, interleukin-15, interleukin-34, and TGF-β; and superoxide dismutase, and a culturing method using same. Furthermore, the regulatory T cells according to the present invention can be utilized for treatment of autoimmune diseases.
机译:本发明涉及一种用于培养外周血单核细胞衍生的调节T细胞的组合物和使用该组合物的调节性T细胞和调节性T细胞培养方法。更具体地,本发明涉及用于培养外周血单核细胞衍生的调节T细胞的组合物,该组合物包含:选自抗CD2,抗CD3,抗CD7,抗CD8的至少一种抗体,抗CD28,抗CD30L,抗CD40,抗CD70,抗CD80,抗CD83和抗CD86;选自白细胞介素-2,白细胞介素-4,白细胞介素-7,白细胞介素-12,白细胞介素-15,白细胞介素-34和TGF-β中的至少一种细胞因子。和超氧化物歧化酶,以及使用该方法的培养方法。此外,根据本发明的调节T细胞可用于治疗自身免疫疾病。

著录项

  • 公开/公告号WO2021060638A1

    专利类型

  • 公开/公告日2021-04-01

    原文格式PDF

  • 申请/专利权人 IMMUNISBIO CO. LTD.;

    申请/专利号WO2020KR04663

  • 发明设计人 HWANG SUNG HWAN;KANG JUNG HWA;

    申请日2020-04-07

  • 分类号C12N5/0783;A61K35/17;A61P37;

  • 国家 KR

  • 入库时间 2022-08-24 18:03:29

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号