2 (PRIME), 3 (PRIME) -PURIC DIDEOXY-NUCLEOSIDES, PREPARATION METHODS, AND ANTIVIRAL AND ANTIRETROVIRAL AGENTS, THERAPEUTIC AND PROPHYLACTIC DRUGS, AND EXPERIMENTAL MEDICINES AND REAGENTS CONTAINING THEM

摘要

This invention relates to novel purine 2 ', 3'-dideoxynucleosides. These compounds are represented by any one of the following general formulas: ## STR2 ## DRAWING IN BOPI) wherein X and Y each represents a carbon atom or a nitrogen atom, and R1, R2, R3, R4 and R5 each independently represent a hydrogen atom or a hydroxyl, amino group , alkyl, halo, alkoxy or mercapto. These compounds are useful as antiviral and antiretroviral agents, especially against HIV, as well as as medicaments and experimental reagents for genetic engineering. The invention has applications in medicine and biology. / P