POLYPEPTIDE P102 DESIGNATED FOR ANTIBODY ASSAY TO HUMAN IMMUNODEFICIENCY VIRUS TYPE-1, DNA HP102-FRAGMENT ENCODING POLYPEPTIDE P102, RECOMBINANT PLASMID DNA PH A102 ENCODING POLYPEPTIDE P102, STRAIN OF BACTERIUM ESCHERICHIA COLI - A PRODUCER OF POLYPEPTIDE P102

摘要

FIELD: biotechnology, genetic engineering, immunology. SUBSTANCE: invention relates to construction of hybrid polypeptide P102 consisting of polypeptide that can bind antibodies to the reverse transcriptase to product of gene pol HIV-1 and $$$-galactosidase of E. coli. Hybrid polypeptide is synthesized by bacterial strain Escherichia coli "ВКПМ" NB-5876. Strain is obtained by transformation of plasmid DNA pH P102 carrying fragment of gene pol HIV-1. EFFECT: construction of polypeptide indicated above.