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Process for removing systematic error and outlier data and for estimating random error in chemical and biological assays
Process for removing systematic error and outlier data and for estimating random error in chemical and biological assays
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机译:在化学和生物学分析中删除系统误差和异常数据以及估计随机误差的过程
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摘要
A method for improving the reliability and/or accuracy of physical measurements obtained from array hybridization studies performed on an array having a large number of genomic samples uses a small number of replicates insufficient for making precise and valid statistical inferences. This is overcome by estimating an error in measurement of a sample by averaging errors obtained when measuring the large number of samples or a subset of the large number of samples. The estimated sample error is utilized as a standard for accepting or rejecting the measurement of the respective sample. The samples may be independent or dependent in that correlated across two or more conditions.
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