METHODS AND NUCLEIC ACID VECTORS FOR RAPID AND PARALLEL ASSAY DEVELOPMENT, FOR CHARACTERIZATION OF BIOLOGICAL RESPONSE MODIFIERS

摘要

A method for utilization of several vectors, cells and combinations of vectors and cells is described; the composition and features of several tripartite vectors that are particularly advantageous is claimed. The methods and vector combinations allow the rapid and parallel establishment of assays that reflect the activity of biological-response-modifiers, including expressed heterologous cDNA or genes. The assays are directly utilizable as screening assays for compounds that modulate the activities of the biological-response-modifiers.