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HIGH-THROUGHPUT METHOD FOR DETERMINING THE ENANTIOMERIC PURITY OF CHIRAL COMPOUNDS

机译:高效液相色谱法测定手性化合物的对映体纯度

摘要

The invention relates to a high-throughput method for determining the enantiomeric purity of chiral compounds, by using electrophoretic separation, with the aid of parallel CE capillaries or microfluidic systems. According to said method, chiral sectors are added to the electrolyte, or the enantiomers to be determined are converted into electrophoretically discernable diastereomers, prior to the electrophoretic separation.
机译:本发明涉及一种高通量方法,该方法借助于电泳分离,借助于平行的CE毛细管或微流体系统,测定手性化合物的对映体纯度。根据所述方法,在电泳分离之前,将手性扇区添加到电解质中,或者将要测定的对映异构体转化成电泳可辨别的非对映异构体。

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