首页>
外国专利>
4,7-DIALKOXY-N-ACETYLNEURAMINIC ACID DERIVATIVES AND METHODS FOR DETECTION OF INFLUENZA TYPE A AND B VIRUSES IN CLINICAL SPECIMENS
4,7-DIALKOXY-N-ACETYLNEURAMINIC ACID DERIVATIVES AND METHODS FOR DETECTION OF INFLUENZA TYPE A AND B VIRUSES IN CLINICAL SPECIMENS
展开▼
机译:4,7-二甲氧基-N-乙酰神经酰胺酸衍生物和临床标本中甲型和乙型流感病毒的检测方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
Chromogenic and fluorogenic 4,7-dialkoxy-N-acetylneuraminic acid substrates of general formula (I) are provided wherein R1 and R2 are alkyl groups containing 1 to 4 carbon atoms and R3 is a chromogenic or fluorogenic group. These substrates can be used to detect influenza types A and B in clinical samples or specimens. More particularly, these 4,7-dialkoxy-N-acetylneuraminic acid substrates can be used to distinguish between various viruses having neuraminidase reactivity. Thus, influenza type A and B viruses can be distinguished from parainfluenza type 1, 2, 3 and 4, and mumps using the 4,7-dialkoxy-N-acetylneuraminic acid derivatives of this invention. Diagnostic methods employing these substrates are provided to identify influenza type A and B viruses in clinical specimens and to distinguish from other viruses having neuraminidase reactivity.
展开▼