Anti-trkc agonist monoclonal antibody, anti-trkc antibody heavy chain, anti-trkc antibody light chain, murine anti-trkc antibody heavy chain, human anti-trkc antibody heavy chain, murine anti-trkc agonist antibody, agonist antibody human anti-trkc, isolated nucleic acid molecules, nucleic acid molecules, vector, host cell lines, hybridoma cell lines, host cell, polypeptide, pharmaceutical composition, method for treating neuropathy or neurodegenerative disease or repair of a injured nerve cell, method for increasing proliferation, maintenance or regeneration of peripheral neurons, method for treating disease or condition involving cell degeneration in a mammalian patient, angiogenesis induction method, method of manufacturing an anti-trkc antibody , uses of an antibody

摘要

"ANTI-trkC AGONIST MONOCLONAL ANTIBODY, ANTI-trkC ANTIBODY HEAVY CHAIN, ANTI-trkC ANTIBODY HEAVY CHAIN, ANTI-trkC MURINO ANTIBODY HEAVY CHAIN, ANTI-TRKC HUMAN ANTIBODY ANTIBODY CHAIN AGONIST ANTI-trkC HUMAN, nucleic acid molecules ISOLATED, nucleic acid molecules, VECTOR, cELLS HOST LINES, LINES OF hYBRIDOMA cELLS, host cell, polypeptide, pHARMACEUTICAL cOMPOSITION, METHOD FOR nEUROPATHY TREATMENT OR DISEASE neurodegenerative OR REPAIR A NERVOUS CELL INJURY, METHOD FOR INCREASING PROLIFERATION, MAINTENANCE OR REGENERATION OF PERIPHERAL NEURIES, METHOD FOR TREATMENT OF DISEASE OR CONDITION INVOLVING AN INTEGRATED CELLULAR DEGENERATION A MALOTIC DEPENDENT trkC AGONIST, USES OF AN ANTIBODY "The present invention relates to anti-t rkc agonists that mimic certain biological activities of NT-3, trkc native ligand. The present invention further relates to the use of such antibodies in the prevention and / or treatment of cell degeneration, including nerve cell damage associated with acute nervous cell system damage and chronic neurodegenerative diseases, including peripheral neuropathy.