Tissue selective androgen receptor modulating compound, composition, pharmaceutical composition, method for binding a selective androgen receptor modulating compound to an androgen receptor, method for modulating spermatogenesis in an individual, method of hormone therapy, method for the treatment for an individual having a hormone-related condition, method for treatment for an individual having prostate cancer and method for determining the presence of a compound

摘要

"COMPOSITION SELECTIVE ANDROGEN RECEIVER MODULATOR COMPOSITION, COMPOSITION, PHARMACEUTICAL COMPOSITION, METHOD FOR CONNECTION OF A SELECTIVE ANDROGEN RECEIVER MODULATOR TO A METHOD AND METHODI ANDROGEN RECEIVER METHOD TREATMENT FOR AN INDIVIDUAL HAVING A HORMONY CONDITION, METHOD FOR TREATING AN INDIVIDUAL HAVING PROSTATIC CANCER AND METHOD FOR DETERMINING THE PRESENCE OF A COMPOUND. " The present invention provides an innovative class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds which are selective tissue androgen receptor modulators (SARMs) which are useful for oral testosterone replacement therapy, male contraception, maintenance of sexual desire in women, treatment of prostate cancer and visualization of prostate cancer. Said agents exhibit unexpected in vivo activity for an androgenic and anabolic activity of a non-steroidal androgen receptor binding agent. Said agents may be active alone or in combination with progestins or estrogens. The invention further provides an innovative class of non-steroidal agonist compounds. The invention further provides compositions containing selective androgen modulating compounds or non-steroidal agonist compounds and methods of binding to an androgen receptor, modulating spermatogenesis, treating and visualizing prostate cancer, and providing hormone therapy for prostate cancer. androgen dependent conditions.