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A process and intermediates for the manufacture of 1- (9H-carbazol-4-yloxy) -3- 2- (2-methoxy-phenoxy) -ethylamino -propan-2-ol, carvedilol and acid addition salts thereof
A process and intermediates for the manufacture of 1- (9H-carbazol-4-yloxy) -3- 2- (2-methoxy-phenoxy) -ethylamino -propan-2-ol, carvedilol and acid addition salts thereof
A new intermediate having the formula (VI) CHEM wherein X and Y are leaving groups; is disclosed. The new intermediate is useful for the preparation of carvedilol in a synthesis that avoids the use of any oxirane or similar hazardous reacgents.
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