首页> 外国专利> A process and intermediates for the manufacture of 1- (9H-carbazol-4-yloxy) -3- 2- (2-methoxy-phenoxy) -ethylamino -propan-2-ol, carvedilol and acid addition salts thereof

A process and intermediates for the manufacture of 1- (9H-carbazol-4-yloxy) -3- 2- (2-methoxy-phenoxy) -ethylamino -propan-2-ol, carvedilol and acid addition salts thereof

机译:制造1-(9H-咔唑-4-基氧基)-3- [2-(2-甲氧基-苯氧基)-乙基氨基]-丙烷-2-醇,卡维地洛及其酸加成盐的方法和中间体

摘要

A new intermediate having the formula (VI) CHEM wherein X and Y are leaving groups; is disclosed. The new intermediate is useful for the preparation of carvedilol in a synthesis that avoids the use of any oxirane or similar hazardous reacgents.
机译:一种具有式(VI)的新中间体,其中X和Y为离去基团;被披露。新的中间体可用于合成卡维地洛,从而避免使用任何环氧乙烷或类似的危险反应物。

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