MODEL ANIMAL FOR ATOPIC DERMATITIS, METHOD FOR SCREENING THERAPEUTIC SUBSTANCE FOR ATOPIC DERMATITIS, AND PHARMACEUTICAL PREPARATION FOR ATOPIC DERMATITIS

摘要

PROBLEM TO BE SOLVED: To provide a model animal for atopic dermatitis suitable for studying and/or diagnosing atopic dermatitis, to provide a method for screening therapeutic substances for atopic dermatitis, and to provide pharmaceutical preparations for atopic dermatitis.;SOLUTION: The model animal for atopic dermatitis is such one that the somatic cells and/or reproductive cells have a recombinant DNA deleted in Stat6 and integrated with an extraneous caspase-1 gene so as to be expressed in a dermally specific way.;COPYRIGHT: (C)2004,JPO