Chromatographic separation of plasma proteins, in particular of factor viii, von willebrand factor, of fibronectin and of fibrinogen.

摘要

The invention relates to a process for the purification of proteins from a fraction of human or animal plasma. / p & & p & according to this process, this fraction or subjected to a chromatographic step on an anion exchange resin of ionic character moderate and allowing the use of hydrophobic interactions which does not absorb certain proteins and fixed on the other, that is then eluted by increasing the ionic strength of the buffer. / p & & p & the implementation of the process of the invention makes it possible to obtain a factor viii concentrate of high purity, which can be used for the treatment of haemophilia.