首页> 外国专利> Method for the determination of the amount of fosfolipu00ecdio Pro coagulant in a sample, the amount of activated platelets and micropartu00ecculas derived from cells in a sample.Method for the production of a plasma substrate for use in the determination of the degree of fosfolipu00ecdio Pro coagulant in a sample.Plasma substrate and kit for the determination of the degree of fosfolipu00ecdio Pro coagulant in a sample.

Method for the determination of the amount of fosfolipu00ecdio Pro coagulant in a sample, the amount of activated platelets and micropartu00ecculas derived from cells in a sample.Method for the production of a plasma substrate for use in the determination of the degree of fosfolipu00ecdio Pro coagulant in a sample.Plasma substrate and kit for the determination of the degree of fosfolipu00ecdio Pro coagulant in a sample.

机译:测定样品中fosfolip u00ecdio Pro凝结剂的量,样品中来源于细胞的活化血小板和微颗粒的量的方法。血浆底物的生产方法样品中的fosfolip u00ecdio Pro凝结剂。血浆基质和试剂盒,用于测定样品中fosfolip u00ecdio Pro凝结剂的程度。

摘要

Method for the determination of the amount of fosfolipu00ecdio Pro coagulant in a sample, the amount of activated platelets and micropartu00ecculas derived from cells in a sample.Method for the production of a plasma substrate for use in the determination of the degree of fosfolipu00ecdio Pro coagulant in a sample.Plasma substrate and kit for the determination of the degree of fosfolipu00ecdio Pro coagulant in a sample.The present invention relates to a method for the determination of the amount of fosfolipu00eddio Pro coagulant in a sample.With the said method comprises the steps of (I) and (III) executed in the following order: (I) the formation of a mixture of the sample and a plasma substrate which has become free or substantially freeOf fosfolipu00eddio Pro coagulant sufficient to reduce at least the capacity of the substrate plasma clotting.In the said plasma substrate became free or substantially free of fosfolipu00eddio Pro coagulant through treatment with a phospholipase; (II) placing the mixture in contact with a reagBetween the activation of plasma coagulation under conditions in which the fosfolipu00eddio Pro coagulant is the limiting component rate of the mixture; and (III) the determination of the coagulation time of the mixture.
机译:测定样品中fosfolip u00ecdio Pro凝结剂的量,样品中来源于细胞的活化血小板和微颗粒的量的方法。血浆底物的生产方法样品中的fosfolip u00ecdio Pro凝结剂。测定样品中fosfolip u00ecdio Pro凝结剂程度的等离子基质和试剂盒。本发明涉及测定样品中fosfolip u00eddio Pro凝结剂含量的方法。所述方法包括按以下顺序执行的步骤(I)和(III):(I)形成样品和血浆基质的混合物,该混合物已经或几乎没有fosfolip u00eddio Pro凝结剂足以至少减少底物血浆凝结的能力。在所述血浆底物中通过用磷脂处理而变得无或基本上不含fosfolip u00eddio Pro凝结剂e; (II)在fosfolip u00eddio Pro凝结剂是混合物的极限成分速率的条件下,使混合物与血浆凝结活化剂接触。 (III)确定混合物的凝结时间。

著录项

  • 公开/公告号BRPI0414293A

    专利类型

  • 公开/公告日2006-11-07

    原文格式PDF

  • 申请/专利权人 HAEMATEX RESEARCH PTY LIMITED;

    申请/专利号BR2004PI14293

  • 发明设计人 THOMAS EXNER;

    申请日2004-09-22

  • 分类号G01N33/86;C12P1/00;C12Q1/34;C12Q1/56;

  • 国家 BR

  • 入库时间 2022-08-21 21:40:00

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