Recombinant canine herpes virus expressing at least one antigen, particularly antigen of canine distemper, rabies, canine parvovirus, and parainfluenza type 2, and vaccine based on such virus

摘要

The present invention relates to vaccines, preferably vaccines for dogs, prepared from canine recombinant herpes viruses. To be specific, it relates to recombinant canine herpes viruses comprising an expression cassette comprising one or several foreign genes wherein the at least one foreign gene encodes an antigen being selected from the group consisting of canine distemper virus HA, canine distemper virus F, rabies virus G, canine parvovirus VP2, parainfluenza virus type 2 HA, parainfluenza virus type 2 F, Borrelia burgdorferi OspA, and Borrelia burgdorferi OspB. The invention further relates to vaccines containing at least one herpes virus according to the present invention.