Indian forest derivatives for the treatment or prevention of fibrotic diseases

摘要

Including indolina type I compounds with a or s; R1 is h or a group of profarmaco; R2 is carboxi, alcoxi c1-c6-carboilo, etc.; R3 is h, C1-C6 tar, C3-C7, etc.; R4 is cycloquilo C3-C7; R6 is h, F, Ciano, amino, etc.; R5 is h, C1-C3 tar, etc. The most popular compounds are: 3-z - [1 - (4 - (piperidin-1-il-met) - anilino) - 1-phenyl-methylene] - 6-etoxicarbonil-2-indolina, 3-z - [(1 - (4 - (piperidin-1-il-methyl) - anilino) - 1-phenyl-methylene] - 6-carbamoil-2-indolina, etc. A pharmaceutical composer was also mentioned These compounds are useful for the treatment or prevention of specific fibroses.