RECEPTOR-BASED RESPIRATORY FORMULATIONS FOR PREVENTION OR MANAGEMENT OF PULMONARY HYPERTENSION OR HYPOXIC HYPOXEMIA AND A PROCESS OF PREPARATION THEREOF

摘要

A respirable formulation where the primary active drugs present in the formulation are one or more of the beta receptor agonists and/or alpha-receptor antagonists, compounds that influence the quantity of drug in the aerosol and the aerosol particle size, in flight or otherwise such as volatile organic compounds, lactose, water or CFC or non-CFC propellants available commercially in the market as the vehicle, reducing substances like ascorbic acid, bicarbonates like sodium bicarbonate to control pH, carrier protiens or peptides, and surfactants, like phosphadil choline and lecithin.