Treatment of inflammation, abeta-induced cell toxicity, neuronal cell death or neuronal cell loss in subjects suffering from alzheimer's disease

摘要

Disclosed are anionic compounds, including 3-amino propansulfonic acid, that are capable of blocking A beta -induced macrophage activation (or macrophage activation induced by other amyloidogenic proteins or peptides). Such compounds can inhibit the inflammatory process, e.g., in the brain of a subject suffering from a disease characterized by A beta deposition, such as Alzheimer's disease.