a composition for the nasal delivery, use of granisetron or a pharmaceutically acceptable salt thereof, and chitosan, a salt, derivative or salt of a derivative thereof, methods of administration of granisetron or a pharmaceutically acceptable salt thereof, and nausea and / or vomiting treatment or prevention, and, nasal drug delivery device or a dose cartridge

摘要

COMPOSITION FOR NASAL DISTRIBUTION, USE OF GRAMSETRON OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND CHITOSANA, A SALT, DERIVATIVE OR SALT OF A SAME DERIVATIVE, METHODS OF ADMINISTRATION OF GRANISETRON EASTERRON, OR TREATMENT OR PREVENTION OF NAUSEA AND / OR VOMITING, AND A DEVICE FOR THE DISTRIBUTION OF THE NOSE DRUG OR A DOSE CARTRIDGE. The present invention provides compositions for intranasal administration of granisetron or a pharmaceutically acceptable salt thereof. Preferred compositions of the invention are in the form of an aqueous solution. Optionally, the compositions of the invention comprise chitosan, a salt or derivative thereof or a salt of a chitosan derivative. The compositions may be used for the treatment or prevention of nausea and / or vomiting.