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THE USE OF MICE PREDISPOSED TO DEVELOP ULCERATIVE COLITIS AND COLON CANCER TO DEVELOP METABOLIC PROFILES ASSOCIATED WITH SAME
THE USE OF MICE PREDISPOSED TO DEVELOP ULCERATIVE COLITIS AND COLON CANCER TO DEVELOP METABOLIC PROFILES ASSOCIATED WITH SAME
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机译:使用预先准备的小鼠发展溃疡性结肠炎和结肠癌来发展与之相关的代谢概况
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摘要
The instant invention is based, at least in part, on the discovery that mice deficient in T-bet develop a form of ulcerative colitis that is transmissible to genetically intact hosts. Accordingly, these animals are useful in the development of metabolic profiles that will enhance the predisposition of a subject to develop ulcerative colitis and/or colon cancer and are useful in the identification of targets for therapeutic intervention.
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