OPTICAL DETECTION OF SEIZURE, A PRE-SEIZURE STATE, AND CEREBRAL EDEMA AND OPTICAL FIBER DETECTION OF THE SAME

摘要

A method for using optical parameters to monitor for a physiological event and/or a state prior to the physiological event includes the steps of: illuminating neural tissue with diagnostic light of a predetermined frequency at a predetermined location; detecting magnitude of optical scattering by neural tissue of the diagnostic light as a function of time; and determining a signature signal of the optical scattering of the diagnostic light before the physiological event in the neural tissue becomes clinically manifested. An apparatus includes a source of diagnostic light of a predetermined frequency for illuminating neural tissue at a predetermined location, a detector of optical scattering and/or optical absorption by neural tissue of the diagnostic light as a function of time, and a signal processor for determining a signature signal of the optical scattering and/or optical absorption of the diagnostic light before the physiological event becomes clinically manifested.