process for the preparation of a composite biomaterial, composite biomaterial, synthetic bone material, bone implant, bone graft, bone substitute, bone structure, filler, lining or cement, and monolithically or layered bone structure for use in tissue engineering

摘要

PROCESS FOR THE PREPARATION OF A COMPOSITE BIOMATERIAL, COMPOSITE BIOMATERIAL, SYNTHETIC BONE MATERIAL, BONE IMPLANT, BONE SUBSTITUTE, BONE STRUCTURE, FILLER, COSING OR ESHUS CUTTING, ESRENOUS CUTTING A process for the preparation of a composite biomaterial comprising an inorganic material and an organic material, the process comprising: (a) providing a first suspension composition comprising a liquid carrier, an inorganic material and an organic material; (b) provide a mold for the suspension; (c) deposit the suspension into the mold; (d) cooling the suspension deposited in the mold to a temperature at which the liquid carrier transforms into a plurality of crystals or solid particles; (e) removing at least some of the plurality of crystals or solid particles by sublimation and / or evaporation to leave a porous composite material comprising an inorganic material and an organic material and (f) removing the material from the mold.