Humanized antibody anti integrin alpha2, method for determining whether a sample contains the integrin alpha2, kit, nucleic acid isolation, vector, host cell, a process for the production of a humanized antibody anti integrin alpha2, screening method, composition, method for tratament The disturbances associated with integrin alfa2beta1 in patients.Method for inhibition of binding of leukocytes to the collagen, method of directing a molecule, the use of a humanized antibody anti integrin alpha2, packaging and epitopo of integrin alpha2 which connects an antibody anti integrin alpha 2

摘要

Humanized antibody anti integrin 244 2, method for determining whether a sample contains the integrin 244 2, kit, nucleic acid isolation, vector, host cell, a process for the production of a humanized antibody anti integrin 244 2, screening method, composition, method for treating Treatment of disturbances associated with integrin 244 2 225 1 in patients.Method for inibiu00e7ao connection of leukocytes to the collagen, method of directing a molecule, the use of a humanized antibody anti integrin 244 2, packaging and epitopo of 4 244 L2 connecting an antibody anti integrin 244 2. This invention relates to antibodies to integrin 244 2 and its uses.Humanized antibodies are described that bind to domain I of the integrin 244 2 and inhibit the interaction of integrin 244 2 225 1 with collagen. Also described are uses of the antibodies to integrin terapeuticos 244 2 in the treatment of disorders mediated by 244 2 225 1, including antibodies to integrin 244 2 which bind to integrin receptors 244 2 without activating platelets.