首页> 外国专利> Bi specific Antibody that specifically binds to human vascular endothelial growth factor (VEGF) and the Human angiopoietin-2 (ang-2); Nucleic Acid encodes it; recombinant expression vector; host Cell method; Antibody Production; Pharmaceutical composition containing same and their use to treat cancer.

Bi specific Antibody that specifically binds to human vascular endothelial growth factor (VEGF) and the Human angiopoietin-2 (ang-2); Nucleic Acid encodes it; recombinant expression vector; host Cell method; Antibody Production; Pharmaceutical composition containing same and their use to treat cancer.

机译：与人血管内皮生长因子（VEGF）和人血管生成素2（ang-2）特异性结合的Bi特异性抗体;核酸编码它;重组表达载体宿主细胞方法;抗体生产;包含其的药物组合物及其在治疗癌症中的用途。

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摘要

The present invention relates to bispecific antibodies against human VEGF and against human ANG-2, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.

机译：本发明涉及针对人VEGF和针对人ANG-2的双特异性抗体，其制备方法，包含所述抗体的药物组合物及其用途。

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公开/公告号CL2011000769A1

专利类型
公开/公告日2011-09-16

原文格式PDF
申请/专利权人 F. HOFFMANN-LA ROCHE AG;
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申请/专利号CL20110000769
发明设计人 REGULA JOERG THOMAS;SCHEUER WERNER;GEORGES GUY;BAEHNER MONIKA;BRINKMANN ULRICH;GRIEP REMKO ALBERT;IMHOF-JUNG SABINE;KAVLIE ANITA;KETTENBERGER HUBERT;KLEIN CHRISTIAN;SCHAEFER WOLFGANG;SCHANZER JUERGEN MICHAEL;SEEBER STEFAN;THOMAS MARKUS;
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申请日2011-04-06
分类号A61K39/395;C07H21/04;C07K14/47;C07K14/475;C12N15/63;C12N5/10;
国家 CL
入库时间 2022-08-21 18:06:57

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