The invention relates to the field of pharmacology, in particular to the new choline cocrystal of epalrestat 5 - [(1Z, 2E) -2-methyl-3-phenylpropenylidene] -4-oxo-2-thioxo-3-thiazolidinacetic acid. A new choline crystal is obtained in accordance with various embodiments of the invention. The invention also relates to pharmaceutical compounds containing a new choline crystal, and is associated with the therapeutic use of a new choline cocrystal for the treatment and / or prevention of various diseases, including the treatment and / or prophylaxis of diabetes complications, the treatment and / or prophylaxis of homocystinuria associated with a decrease in homocysteine in serum, inhibition of aldose reductase, as well as the creation of a cardioprotective effect in patients without diabetes.
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