CRYSTALLINE FORMS OF 5-AMINO-2,3-DIHYDROPHTHALAZINE-1,4-DIONE SODIUM SALT, PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME, METHOD FOR PRODUCTION OF SAID FORMS AND USE OF SAID FORMS FOR MODULATING THE IMMUNE SYSTEM

摘要

The invention relates to the provision of two novel crystalline forms I and II for 5-amino-2,3-dihydrophthalazine-1,4-dione sodium salt. Surprisingly it was discovered that form I and form II have differing immunological effects. This advantageous property is useful for immune-specific applications. In addition, both forms have advantageous physicochemical properties which are useful in the production, further processing and/or use of a pharmaceutical preparation of form I, form II or a mixture of both.